Franz diffusion cell operation and conditions
Franz diffusion cells | Condition |
---|---|
Instrument | DHC-6TD, Logan |
Skin | Strat-M membrane |
Area of skin | 2.5 cm3 |
Volume of sample solution | 0.5 mL |
Receptor medium | 2% polysorbate 20 in 20% EtOH |
Temperature | 37°C |
Stir bar speed | 600 rpm |
Sampling aliquot | 12 mL |
Sampling time | 1, 2, 4, 8, 12, 24 h |