Fig. 7. Effects of CME on p-GSK-3β and β-catenin expressions in vivo. (a) H&E staining and TUNEL assay of apoptosis cells in tumor tissue. (b) The levels of p-GSK-3β and β-catenin were also measured by immunohistochemical analysis. The slides were observed under a microscope (magnification, x100 and x400) and images were captured. Black circle indicate cytosolic p-GSK-3β and yellow arrows indicate nuclear accumulation of β-catenin. CME, Cnidium monnieri (L.) Cusson extract; H&E, Hematoxylin and eosin; TUNEL, terminal deoxynucleotidyl-transferase-mediated dUTP nick end labelling; GSK-3β, glycogen synthase kinase-3β.
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